The Acura MDX and the Lexus RX are both impressive luxury three-row midsize SUVs, but there is a clear frontrunner between the two. To help you choose between these two vehicles, our team at Maus Acura created this guide to the differences between the 2022 Acura MDX and the 2021 Lexus RX. Scroll down to compare!


The Acura MDX has a 3.5-liter V6 engine wit 290 horsepower and a max towing capacity of up to 5,000 lbs! Paired with a double-wishbone suspension, when driving the MDX you have outstanding muscle and control. Plus, with torque vectoring, exclusive to the available Super Handling All-Wheel Drive, you can channel incredible power to improve handling in almost any condition.

When you want to take manual control, standard paddle shifters put 10 gear ratios in your hands. Handling of the MDX is enhanced by the Integrated Dynamics System and available wider 20-in alloy wheels which give the MDX an adrenaline-inducing performance.

The 2021 Lexus RX may look like a luxury sports SUV but it's built for comfort, not for speed. It does come with the standard V6 with 295 horsepower, but the Adaptive Variable Suspension which helps reduce body lean through curves and improves overall ride comfort is only available on the Sport trim.  The towing capacity of the Lexus Rx is 3,500 lbs and comes with 18-inch alloy wheels.


The Acura MDX has seven seats, and with the Advance Package, you will receive an abundance of amenities including a navigation system, hands-free power tailgate, and a panoramic moonroof. The comfortable front seats are heated and ventilated, and perforated Milano leather throughout the luxury SUV keeps everyone, from the driver to the third row, riding in comfort. Plus, second-row passengers can enjoy heated outboard seating.

Plus, the digital Precision Cockpit™ in the Acura MDX  puts all your driving information front and center in brilliant HD. Plus, you can immerse yourself in a bespoke atmosphere with the available Iconic Drive™ Ambient Cabin Lighting!

While the Lexus RX has luxurious  touches in its cabin, it feels cramped and "walls off" the passengers from the driver. Plus, with the base RX trim, you can only seat five people comfortably, though the other trim levels can seat six or seven.

Infotainment System

The MDX is equipped with an ultra-refined, technologically advanced cabin. The dashboard has a 12.3-in HD Center Display, which is the widest screen ever to be featured in an Acura. The MDX also comes with a multi-view rear camera, music, and available navigation that are easily controlled via the True Touchpad Interface™.

Other tech features in the Acura MDX include:

  • Apple CarPlay
  • Siri Eyes Free
  • Android Auto Integration
  • Alexa Built-In
  • Acura/ELS STUDIO 3D®  audio system

The Lexus Rx also comes with Apple CarPlay and Alexa compatibility and other tech features, but its touchscreen is only 8.0 inches.


The 2022 Acura MDX is equipped with a suite of cutting-edge safety and driver-assistive technologies that help heighten driver awareness, avoid collisions, and reduce the severity of impacts. Besides multiple airbags, a LATCH system, an antilock braking system, tire pressure monitor system, and vehicle stability assist, the Acura MDX has numerous other safety features.

The following safety features come standard on the Acura MDX:

  • Collision Mitigation Braking System™
  • Road Departure Mitigation
  • Adaptive Cruise Control with Low-Speed Follow
  • Lane Keeping Assist System
  • Pedestrian Detection
  • Traffic Sign Recognition
  • Traffic Jam Assist

Plus these available safety technologies:

  • Surround-View Camera
  • Blind Spot Information System
  • Rear Cross Traffic Monitor
  • Low-Speed Braking Control

Though the Lexus RX has many comparable safety features, it has mixed crash test results, which undermines these safety features.

Test Drive a Luxury Midsize SUV at Maus Acura

The 2022 Acura MDX far outperforms the 2021 Lexus RX 350L in so many ways. While the Lexus RX and the 2022 Acura MDX are both impressive midsize SUVs, as you can see, the powerful 2022 Acura MDX reigns superior.

Why settle for the Lexus RX  when you can enjoy the thrill of the ride with the 2022 Acura MDX? It's MDX for the win! Call Maus Acura of North Tampa to schedule a test drive today!

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Maus Acura of North Tampa

11025 N Florida Ave
Directions Tampa, FL 33612

  • Sales: 813-669-4684
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